Down-Regulation of PU.1 Gene in Pediatric Acute Lymphoblastic Leukemia Patients from South of Iran

Down-Regulation of PU.1 Gene in Pediatric Acute Lymphoblastic Leukemia Patients from South of Iran

Background: Acute lymphoblastic leukemia (ALL) is resulted from the infiltration of high amount of non-differentiated cells in bone marrow. Differentiation of the hematopoietic stem cells into specific cell lineage occurs through a highly regulated pathway which is mainly monitored during transcrip...

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Bibliographic Details
Main Authors: Bita Nakhost, Mahboobeh Nasiri, Mehran Karimi, Somayeh Montazeri
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2019-01-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Pediatric ALL; PU.1; Gene expression
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/924

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