DUSP1 Blocks autophagy-dependent ferroptosis in pancreatic cancer

DUSP1 Blocks autophagy-dependent ferroptosis in pancreatic cancer

Abstract. Ferroptosis is a oxidative damage-dependent form of regulated cell death that has become an emerging target for disease prevention and treatment. Here, we show that dual-specificity phosphatase 1 (DUSP1), a phosphatase playing multiple roles in stress-signaling pathways, is a new repressor...

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Bibliographic Details
Main Authors: Yangchun Xie, Feimei Kuang, Jiao Liu, Daolin Tang, MD, Rui Kang
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2020-09-01
Series:Journal of Pancreatology
Online Access:http://journals.lww.com/10.1097/JP9.0000000000000054

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