Exogenous glucose administration impairs glucose tolerance and pancreatic insulin secretion during acute sepsis in non-diabetic mice.

Exogenous glucose administration impairs glucose tolerance and pancreatic insulin secretion during acute sepsis in non-diabetic mice.

OBJECTIVES:The development of hyperglycemia and the use of early parenteral feeding are associated with poor outcomes in critically ill patients. We therefore examined the impact of exogenous glucose administration on the integrated metabolic function of endotoxemic mice using our recently developed...

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Bibliographic Details
Main Authors: Yoshio Watanabe, Srikanth Singamsetty, Baobo Zou, Lanping Guo, Darko Stefanovski, Laura C Alonso, Adolfo Garcia-Ocana, Christopher P O'Donnell, Bryan J McVerry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3691245?pdf=render

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