miR-107 activates ATR/Chk1 pathway and suppress cervical cancer invasion by targeting MCL1.

miR-107 activates ATR/Chk1 pathway and suppress cervical cancer invasion by targeting MCL1.

MicroRNAs (miRNAs) are a class of single-stranded, non-coding RNAs of about 22 nucleotides in length. Increasing evidence implicates miRNAs may function as oncogenes or tumor suppressors. Here we showed that miR-107 directly targeted MCL1 and activated ATR/Chk1 pathway to inhibit proliferation, migr...

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Bibliographic Details
Main Authors: Chengyan Zhou, Gang Li, Jingjing Zhou, Na Han, Zhihui Liu, Jun Yin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4227659?pdf=render

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http://europepmc.org/articles/PMC4227659?pdf=render

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