ATP-Binding Cassette Transporters Modulate Both Coelenterazine- and D-Luciferin-Based Bioluminescence Imaging
Bioluminescence imaging (BLI) of luciferase reporters provides a cost-effective and sensitive means to image biological processes. However, transport of luciferase substrates across the cell membrane does affect BLI readout intensity from intact living cells. To investigate the effect of ATP-binding...
Main Authors: | Ruimin Huang, Jelena Vider, Inna Serganova, Ronald G. Blasberg |
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Format: | Article |
Language: | English |
Published: |
Hindawi - SAGE Publishing
2011-05-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2010.00045 |
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