DNMT3B7 expression promotes tumor progression to a more aggressive phenotype in breast cancer cells.

DNMT3B7 expression promotes tumor progression to a more aggressive phenotype in breast cancer cells.

Epigenetic changes, such as DNA methylation, have been shown to promote breast cancer progression. However, the mechanism by which cancer cells acquire and maintain abnormal DNA methylation is not well understood. We have previously identified an aberrant splice form of a DNA methyltransferase, DNMT...

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Bibliographic Details
Main Authors: Patrick R Brambert, Daniel J Kelpsch, Rabia Hameed, Charmi V Desai, Gianfranco Calafiore, Lucy A Godley, Stacey L Raimondi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4301645?pdf=render

Internet

http://europepmc.org/articles/PMC4301645?pdf=render

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