Chronic kidney disease in the emergency centre: A prospective observational study

Introduction: Late presentation, usually to the emergency centre (EC), is frequently reported among patients with chronic kidney disease (CKD) in resource-limited settings, and is known to be associated with poor outcomes. This study aims to describe the pattern of EC presentation of adults with CKD...

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Main Authors: Babawale Taslim Bello, Olalekan Ezekiel Ojo, Olapeju Funke Oguntunde, Adedotun Ademola Adegboye
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:African Journal of Emergency Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2211419X17301052
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spelling doaj-6900f71b05f547d4a0d8da391456a38e2020-11-25T00:39:57ZengElsevierAfrican Journal of Emergency Medicine2211-419X2018-12-0184134139Chronic kidney disease in the emergency centre: A prospective observational studyBabawale Taslim Bello0Olalekan Ezekiel Ojo1Olapeju Funke Oguntunde2Adedotun Ademola Adegboye3Department of Medicine, College of Medicine, University of Lagos, Idi-Araba, Lagos, Nigeria; Corresponding author.Department of Medicine, Federal Medical Center, Owo, NigeriaDepartment of Medicine, Lagos University Teaching Hospital, Idi-Araba, Lagos, NigeriaDepartment of Medicine, Federal Medical Center, Owo, NigeriaIntroduction: Late presentation, usually to the emergency centre (EC), is frequently reported among patients with chronic kidney disease (CKD) in resource-limited settings, and is known to be associated with poor outcomes. This study aims to describe the pattern of EC presentation of adults with CKD in Southwest Nigeria. Methods: This was a prospective observational study of 158 consecutively presenting CKD patients at the EC of two tertiary hospitals in Southwest Nigeria. Patients 18 years of age or older who were admitted into the EC at either study site with an admitting diagnosis of CKD and who consented to participate in the study were recruited. Socio-demographic characteristics, primary reason(s) for admission into the EC, requirement for dialysis, as well as the indication for dialysis were documented. The patients were followed-up for the duration of their stay in the EC and the outcome of EC admission documented. Results: Overall, 54 (34.2%) were females, median age was 49 years and 74.1% were not known to have CKD prior to EC admission. The commonest indications for admission into the EC were uraemia, sepsis and hypertensive crisis, with 73.4% of the patients having at least one indication for dialysis at EC admission. The commonest indications for dialysis were uraemia, marked azotaemia and acute pulmonary oedema. The median time to first session of dialysis was 48 h and 24.1% of patients who required dialysis were not dialysed. Death during the period of EC admission occurred in 14 (8.9%) patients all of whom were not previously known to have CKD. Discussion: There is a large pool of undiagnosed CKD among the general population. In many of these, the diagnosis will likely be made only when they present to the EC with complications. Late diagnosis is associated with worse outcomes. Keywords: Chronic Kidney Disease, Late Presentation, Emergency Centre in the Article Info Sectionhttp://www.sciencedirect.com/science/article/pii/S2211419X17301052
collection DOAJ
language English
format Article
sources DOAJ
author Babawale Taslim Bello
Olalekan Ezekiel Ojo
Olapeju Funke Oguntunde
Adedotun Ademola Adegboye
spellingShingle Babawale Taslim Bello
Olalekan Ezekiel Ojo
Olapeju Funke Oguntunde
Adedotun Ademola Adegboye
Chronic kidney disease in the emergency centre: A prospective observational study
African Journal of Emergency Medicine
author_facet Babawale Taslim Bello
Olalekan Ezekiel Ojo
Olapeju Funke Oguntunde
Adedotun Ademola Adegboye
author_sort Babawale Taslim Bello
title Chronic kidney disease in the emergency centre: A prospective observational study
title_short Chronic kidney disease in the emergency centre: A prospective observational study
title_full Chronic kidney disease in the emergency centre: A prospective observational study
title_fullStr Chronic kidney disease in the emergency centre: A prospective observational study
title_full_unstemmed Chronic kidney disease in the emergency centre: A prospective observational study
title_sort chronic kidney disease in the emergency centre: a prospective observational study
publisher Elsevier
series African Journal of Emergency Medicine
issn 2211-419X
publishDate 2018-12-01
description Introduction: Late presentation, usually to the emergency centre (EC), is frequently reported among patients with chronic kidney disease (CKD) in resource-limited settings, and is known to be associated with poor outcomes. This study aims to describe the pattern of EC presentation of adults with CKD in Southwest Nigeria. Methods: This was a prospective observational study of 158 consecutively presenting CKD patients at the EC of two tertiary hospitals in Southwest Nigeria. Patients 18 years of age or older who were admitted into the EC at either study site with an admitting diagnosis of CKD and who consented to participate in the study were recruited. Socio-demographic characteristics, primary reason(s) for admission into the EC, requirement for dialysis, as well as the indication for dialysis were documented. The patients were followed-up for the duration of their stay in the EC and the outcome of EC admission documented. Results: Overall, 54 (34.2%) were females, median age was 49 years and 74.1% were not known to have CKD prior to EC admission. The commonest indications for admission into the EC were uraemia, sepsis and hypertensive crisis, with 73.4% of the patients having at least one indication for dialysis at EC admission. The commonest indications for dialysis were uraemia, marked azotaemia and acute pulmonary oedema. The median time to first session of dialysis was 48 h and 24.1% of patients who required dialysis were not dialysed. Death during the period of EC admission occurred in 14 (8.9%) patients all of whom were not previously known to have CKD. Discussion: There is a large pool of undiagnosed CKD among the general population. In many of these, the diagnosis will likely be made only when they present to the EC with complications. Late diagnosis is associated with worse outcomes. Keywords: Chronic Kidney Disease, Late Presentation, Emergency Centre in the Article Info Section
url http://www.sciencedirect.com/science/article/pii/S2211419X17301052
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