Detection of phospho-sites generated by protein kinase CK2 in CFTR: mechanistic aspects of Thr1471 phosphorylation.

Detection of phospho-sites generated by protein kinase CK2 in CFTR: mechanistic aspects of Thr1471 phosphorylation.

By mass spectrometry analysis of mouse Cystic Fibrosis Transmembrane-conductance Regulator (mCFTR) expressed in yeast we have detected 21 phosphopeptides accounting for 22 potential phospho-residues, 12 of which could be unambiguously assigned. Most are conserved in human CFTR (hCFTR) and the majori...

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Main Authors: Andrea Venerando, Cinzia Franchin, Natasha Cant, Giorgio Cozza, Mario A Pagano, Kendra Tosoni, Ateeq Al-Zahrani, Giorgio Arrigoni, Robert C Ford, Anil Mehta, Lorenzo A Pinna
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3776838?pdf=render

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