<b>Reactions of 5-[1-(2-phenyl)methylidene]-3-phenylimidazolidine-2,4-diones with some organometallic reagents</b>
The reaction of Grignard reagents with 5-[1-(2-chlorophenyl)methylidene]-3-phenylimidazolidine-2,4-dione, <b>4</b>, and 5-[1-(2-bromophenyl)methylidene]-3-phenylimidazolidine-2,4-dione, <b>5</b>, gave exclusively 1,2-addition products, <b>6-8</b>, in 70-80% yields...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Chemical Society of Ethiopia
2005-06-01
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Series: | Bulletin of the Chemical Society of Ethiopia |
Subjects: | |
Online Access: | http://www.ajol.info/index.php/bcse/article/view/21109 |
Summary: | The reaction of Grignard reagents with 5-[1-(2-chlorophenyl)methylidene]-3-phenylimidazolidine-2,4-dione, <b>4</b>, and 5-[1-(2-bromophenyl)methylidene]-3-phenylimidazolidine-2,4-dione, <b>5</b>, gave exclusively 1,2-addition products, <b>6-8</b>, in 70-80% yields. Lithium dibutylcuprate reacted with <b>4</b> to yield exclusively 1,2-addition product <b>9</b> (92%). No conjugate or 1,4-addition products were obtained. These results indicate that 5-[1-(2-phenyl)methylidene]-3-phenylimidazolidine-2,4-diones do not react like normal unsaturated carbonyl compounds. |
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ISSN: | 1011-3924 1726-801X |