<b>Reactions of 5-[1-(2-phenyl)methylidene]-3-phenylimidazolidine-2,4-diones with some organometallic reagents</b>

The reaction of Grignard reagents with 5-[1-(2-chlorophenyl)methylidene]-3-phenylimidazolidine-2,4-dione, <b>4</b>, and 5-[1-(2-bromophenyl)methylidene]-3-phenylimidazolidine-2,4-dione, <b>5</b>, gave exclusively 1,2-addition products, <b>6-8</b>, in 70-80% yields...

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Bibliographic Details
Main Authors: Teresa A. R. Akeng'a, Roger W. Read
Format: Article
Language:English
Published: Chemical Society of Ethiopia 2005-06-01
Series:Bulletin of the Chemical Society of Ethiopia
Subjects:
1
Online Access:http://www.ajol.info/index.php/bcse/article/view/21109
Description
Summary:The reaction of Grignard reagents with 5-[1-(2-chlorophenyl)methylidene]-3-phenylimidazolidine-2,4-dione, <b>4</b>, and 5-[1-(2-bromophenyl)methylidene]-3-phenylimidazolidine-2,4-dione, <b>5</b>, gave exclusively 1,2-addition products, <b>6-8</b>, in 70-80% yields. Lithium dibutylcuprate reacted with <b>4</b> to yield exclusively 1,2-addition product <b>9</b> (92%). No conjugate or 1,4-addition products were obtained. These results indicate that 5-[1-(2-phenyl)methylidene]-3-phenylimidazolidine-2,4-diones do not react like normal unsaturated carbonyl compounds.
ISSN:1011-3924
1726-801X