The Aspergillus fumigatus cell wall integrity signalling pathway: drug target, compensatory pathways and virulence

Aspergillus fumigatus is the most important airborne fungal pathogen, causing severe infections with invasive growth in immunocompromised patients. The fungal cell wall prevents the cell from lysing and protects the fungus against environmental stress conditions. Because it is absent in humans and b...

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Bibliographic Details
Main Authors: Vito eValiante, Juliane eMacheleidt, Martin eFöge, Axel A Brakhage
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00325/full