Transduction of Pig Small Airway Epithelial Cells and Distal Lung Progenitor Cells by AAV4

Transduction of Pig Small Airway Epithelial Cells and Distal Lung Progenitor Cells by AAV4

Cystic fibrosis (CF) is caused by genetic mutations of the CF transmembrane conductance regulator (CFTR), leading to disrupted transport of Cl<sup>−</sup> and bicarbonate and CF lung disease featuring bacterial colonization and chronic infection in conducting airways. CF pigs engineered...

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Bibliographic Details
Main Authors: Oliver G. Chen, Steven E. Mather, Christian M. Brommel, Bradley A. Hamilton, Annie Ehler, Raul Villacreses, Reda E. Girgis, Mahmoud Abou Alaiwa, David A. Stoltz, Joseph Zabner, Xiaopeng Li
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
cystic fibrosis 1
CFTR
small airway epithelia
progenitor cells
AAV4
Online Access:https://www.mdpi.com/2073-4409/10/5/1014

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