<i>In Silico</i> Insights into HIV-1 Vpu-Tetherin Interactions and Its Mutational Counterparts

Tetherin, an interferon-induced host protein encoded by the bone marrow stromal antigen 2 (BST2/CD317/HM1.24) gene, is involved in obstructing the release of many retroviruses and other enveloped viruses by cross-linking the budding virus particles to the cell surface. This activity is antagonized i...

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Bibliographic Details
Main Authors: Patil Sneha, Urmi Shah, Seetharaman Balaji
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Medical Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3271/7/6/74