Stem cell characteristics promote aggressiveness of diffuse large B-cell lymphoma

Abstract Diffuse large B-cell lymphoma (DLBCL) may present initially in bone marrow, liver and spleen without any lymphadenopathy (referred to as BLS-type DLBCL), which is aggressive and frequently associated with hemophagocytic syndrome. Its tumorigenesis and molecular mechanisms warrant clarificat...

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Bibliographic Details
Main Authors: Kung-Chao Chang, Ruo-Yu Chen, Yu-Chu Wang, Liang-Yi Hung, L. Jeffrey Medeiros, Ya-Ping Chen, Tsai-Yun Chen, Jui-Chu Yang, Po-Min Chiang
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78508-7

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