Suppression of Notch Signaling Stimulates Progesterone Synthesis by Enhancing the Expression of NR5A2 and NR2F2 in Porcine Granulosa Cells

The conserved Notch pathway is reported to be involved in progesterone synthesis and secretion; however, the exact effects remain controversial. To determine the role and potential mechanisms of the Notch signaling pathway in progesterone biosynthesis in porcine granulosa cells (pGCs), we first used...

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Bibliographic Details
Main Authors: Rihong Guo, Fang Chen, Zhendan Shi
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/11/2/120