Effect of fatty acid modification on prostaglandin production by cultured 3T3 cells.

We have investigated the extent to which modifications in the essential fatty acid content of mammalian cells can affect prostaglandin production. Swiss mouse 3T3 cells stimulated with the calcium ionophore A23187 produced 1.7 to 7 times more prostaglandin E(2) (PGE(2)) when the cultures were supple...

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Bibliographic Details
Main Authors: G M Denning, P H Figard, A A Spector
Format: Article
Language:English
Published: Elsevier 1982-05-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520381220