Left Atrial Appendage Closure for Stroke Prevention in Patients with Atrial Fibrillation and Hereditary Hemorrhagic Telangiectasia

Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting millions of individuals worldwide, and a major risk factor for disabling cerebral embolic stroke. Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant inherited disorder, characterized by vascular abnormalities...

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Main Authors: Sebastiaan Velthuis, Martin J. Swaans, Johannes J. Mager, Benno J. W. M. Rensing, Lucas V. A. Boersma, Martijn C. Post
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2012/646505
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spelling doaj-68be4cce44c24519940ea9b40cb165232020-11-24T22:26:54ZengHindawi LimitedCase Reports in Cardiology2090-64042090-64122012-01-01201210.1155/2012/646505646505Left Atrial Appendage Closure for Stroke Prevention in Patients with Atrial Fibrillation and Hereditary Hemorrhagic TelangiectasiaSebastiaan Velthuis0Martin J. Swaans1Johannes J. Mager2Benno J. W. M. Rensing3Lucas V. A. Boersma4Martijn C. Post5Department of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The NetherlandsDepartment of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The NetherlandsDepartment of Pulmonology, St. Antonius Hospital, 3435 CM Nieuwegein, The NetherlandsDepartment of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The NetherlandsDepartment of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The NetherlandsDepartment of Cardiology, St. Antonius Hospital, 3435 CM Nieuwegein, The NetherlandsAtrial fibrillation (AF) is the most common cardiac arrhythmia, affecting millions of individuals worldwide, and a major risk factor for disabling cerebral embolic stroke. Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant inherited disorder, characterized by vascular abnormalities with high-bleeding tendency and therefore intolerance for oral anticoagulation. We report a case of percutaneous closure of the left atrial appendage, which might be a good alternative strategy instead of chronic oral anticoagulation to protect patients with high-risk AF and HHT from cerebral embolic strokes.http://dx.doi.org/10.1155/2012/646505
collection DOAJ
language English
format Article
sources DOAJ
author Sebastiaan Velthuis
Martin J. Swaans
Johannes J. Mager
Benno J. W. M. Rensing
Lucas V. A. Boersma
Martijn C. Post
spellingShingle Sebastiaan Velthuis
Martin J. Swaans
Johannes J. Mager
Benno J. W. M. Rensing
Lucas V. A. Boersma
Martijn C. Post
Left Atrial Appendage Closure for Stroke Prevention in Patients with Atrial Fibrillation and Hereditary Hemorrhagic Telangiectasia
Case Reports in Cardiology
author_facet Sebastiaan Velthuis
Martin J. Swaans
Johannes J. Mager
Benno J. W. M. Rensing
Lucas V. A. Boersma
Martijn C. Post
author_sort Sebastiaan Velthuis
title Left Atrial Appendage Closure for Stroke Prevention in Patients with Atrial Fibrillation and Hereditary Hemorrhagic Telangiectasia
title_short Left Atrial Appendage Closure for Stroke Prevention in Patients with Atrial Fibrillation and Hereditary Hemorrhagic Telangiectasia
title_full Left Atrial Appendage Closure for Stroke Prevention in Patients with Atrial Fibrillation and Hereditary Hemorrhagic Telangiectasia
title_fullStr Left Atrial Appendage Closure for Stroke Prevention in Patients with Atrial Fibrillation and Hereditary Hemorrhagic Telangiectasia
title_full_unstemmed Left Atrial Appendage Closure for Stroke Prevention in Patients with Atrial Fibrillation and Hereditary Hemorrhagic Telangiectasia
title_sort left atrial appendage closure for stroke prevention in patients with atrial fibrillation and hereditary hemorrhagic telangiectasia
publisher Hindawi Limited
series Case Reports in Cardiology
issn 2090-6404
2090-6412
publishDate 2012-01-01
description Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting millions of individuals worldwide, and a major risk factor for disabling cerebral embolic stroke. Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant inherited disorder, characterized by vascular abnormalities with high-bleeding tendency and therefore intolerance for oral anticoagulation. We report a case of percutaneous closure of the left atrial appendage, which might be a good alternative strategy instead of chronic oral anticoagulation to protect patients with high-risk AF and HHT from cerebral embolic strokes.
url http://dx.doi.org/10.1155/2012/646505
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