Myeloid cell leukemia-1 (<it>Mc1</it>-<it>1</it>) is a candidate target gene of hypoxia-inducible factor-1 (<it>HIF</it>-<it>1</it>) in the testis

Myeloid cell leukemia-1 (<it>Mc1</it>-<it>1</it>) is a candidate target gene of hypoxia-inducible factor-1 (<it>HIF</it>-<it>1</it>) in the testis

<p>Abstract</p> <p>Background</p> <p>Spermatic cord torsion can lead to testis ischemia (I) and subsequent ischemia-reperfusion (I/R) causing germ cell-specific apoptosis. Previously, we demonstrated that the hypoxia-inducible factor-1 (HIF-1) transcription factor, a ke...

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Bibliographic Details
Main Authors: Palladino Michael A, Shah Anoop, Tyson Rebecca, Horvath Jaclyn, Dugan Christine, Karpodinis Marie
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Reproductive Biology and Endocrinology
Subjects:
Apoptosis
Torsion
Ischemia
Leydig cells
Online Access:http://www.rbej.com/content/10/1/104

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