The importance of mechanical constraints for proper polarization and psuedo-cleavage furrow generation in the early Caenorhabditis elegans embryo.

Intracellular polarization, where a cell specifies a spatial axis by segregation of specific factors, is a fundamental biological process. In the early embryo of the nematode worm Caenorhabditis elegans (C. elegans), polarization is often accompanied by deformations of the cortex, a highly contracti...

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Bibliographic Details
Main Authors: Betül Senay Aras, Y C Zhou, Adriana Dawes, Ching-Shan Chou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC6053242?pdf=render