KDT501, a derivative from hops, normalizes glucose metabolism and body weight in rodent models of diabetes.
AIMS/HYPOTHESIS: We developed KDT501, a novel substituted 1,3-cyclopentadione chemically derived from hop extracts, and evaluated it in various in vitro and in vivo models of diabetes and insulin sensitivity. METHODS: KDT501 was evaluated for anti-inflammatory effects in monocyte/macrophage cells; a...
Main Authors: | Veera R Konda, Anuradha Desai, Gary Darland, Neile Grayson, Jeffrey S Bland |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3907559?pdf=render |
Similar Items
-
The Influence of a KDT501, a Novel Isohumulone, on Adipocyte Function in Humans
by: Brian S. Finlin, et al.
Published: (2017-09-01) -
<it>Rho </it>iso-alpha acids from hops inhibit the GSK-3/NF-κB pathway and reduce inflammatory markers associated with bone and cartilage degradation
by: Bland Jeffrey S, et al.
Published: (2009-08-01) -
KDT
by: Betty Masruroh
Published: (2018-07-01) -
KDT
by: betty masruroh
Published: (2015-01-01) -
KDT
by: r r
Published: (2019-01-01)