Mitogen-activated protein kinase phosphatase 1 protects PC12 cells from amyloid beta-induced neurotoxicity

Mitogen-activated protein kinase phosphatase 1 protects PC12 cells from amyloid beta-induced neurotoxicity

The mitogen-activated protein kinase (MAPK) signaling pathway plays an important role in the regulation of cell growth, proliferation, differentiation, transformation and death. Mitogen-activated protein kinase phosphatase 1 (MKP1) has an inhibitory effect on the p38MAPK and JNK pathways, but it is...

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Bibliographic Details
Main Authors: Yue Gu, Lian-Jun Ma, Xiao-Xue Bai, Jing Jie, Xiu-Fang Zhang, Dong Chen, Xiao-Ping Li
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; mitogen-activated protein kinase phosphatase 1; c-Jun N-terminal kinase signaling pathway; Alzheimer′s disease; neurons; dementia; apoptosis; RNA interference; lentivirus; inflammation; oxidative stress; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=10;spage=1842;epage=1850;aulast=Gu

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