Genetic mechanisms in Apc-mediated mammary tumorigenesis.

Genetic mechanisms in Apc-mediated mammary tumorigenesis.

Many components of Wnt/beta-catenin signaling pathway also play critical roles in mammary tumor development, yet the role of the tumor suppressor gene APC (adenomatous polyposis coli) in breast oncongenesis is unclear. To better understand the role of Apc in mammary tumorigenesis, we introduced cond...

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Bibliographic Details
Main Authors: Mari Kuraguchi, Nana Yaw Ohene-Baah, Dmitriy Sonkin, Roderick Terry Bronson, Raju Kucherlapati
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2629572?pdf=render

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