IL-1β-Induced Mesenchymal Stem Cell Migration Involves MLCK Activation via PKC Signaling

IL-1β-Induced Mesenchymal Stem Cell Migration Involves MLCK Activation via PKC Signaling

Mesenchymal stem cells (MSCs) migrate via the bloodstream to sites of injury, possibly attracted by inflammatory cytokines. Although many cytokines can induce stem cell migration, the underlying mechanism is not fully understood. We found that tail vein-injected MSCs migrate to the pancreas in nonob...

Full description

Bibliographic Details
Main Authors:	Cheng-Yu Lin, Chia-Hua Zu, Chih-Chang Yang, Pei-Jiun Tsai, Jia-Fwu Shyu, Chie-Pein Chen, Zen-Chung Weng, Tien-Hua Chen M.D., Hwai-Shi Wang Ph.D.
Format:	Article
Language:	English
Published:	SAGE Publishing 2015-10-01
Series:	Cell Transplantation
Online Access:	https://doi.org/10.3727/096368914X685258

Similar Items

IL-1β-Induced Matrix Metalloprotease-1 Promotes Mesenchymal Stem Cell Migration via PAR1 and G-Protein-Coupled Signaling Pathway
by: Ming-Siou Chen, et al.
Published: (2018-01-01)

The Effects of Lactobacillus acidophilus on the Intestinal Smooth Muscle Contraction through PKC/MLCK/MLC Signaling Pathway in TBI Mouse Model.
by: Bo Sun, et al.
Published: (2015-01-01)

Transplantation of insulin-producing cells from umbilical cord mesenchymal stem cells for the treatment of streptozotocin-induced diabetic rats
by: Tsai Pei-Jiun, et al.
Published: (2012-04-01)

Interleukin-1β induces CXCR3-mediated chemotaxis to promote umbilical cord mesenchymal stem cell transendothelial migration
by: Yu-Chien Guo, et al.
Published: (2018-10-01)

Comparisons of Differentiation Potential in Human Mesenchymal Stem Cells from Wharton’s Jelly, Bone Marrow, and Pancreatic Tissues
by: Shih-Yi Kao, et al.
Published: (2015-01-01)

Data on the negative regulation of invadopodia activity by MLCK
by: Rachel J. Jerrell, et al.
Published: (2019-06-01)

Sodium Butyrate Promotes Reassembly of Tight Junctions in Caco-2 Monolayers Involving Inhibition of MLCK/MLC2 Pathway and Phosphorylation of PKCβ2
by: Wei Miao, et al.
Published: (2016-10-01)

Transplantation of Insulin-Producing Cells Derived from Umbilical Cord Stromal Mesenchymal Stem Cells to Treat NOD Mice
by: Hwai-Shi Wang, et al.
Published: (2011-04-01)

Study on the correlation of MLCK and FAP expression with uterine fibroid cell proliferation and invasion
by: Wei Lin1, et al.
Published: (2017-06-01)

Interleukin-1β-induced matrix metalloproteinase-3 via ERK1/2 pathway to promote mesenchymal stem cell migration.
by: Chun-Hao Chang, et al.
Published: (2021-01-01)

IgE regulates the expression of smMLCK in human airway smooth muscle cells.
by: Jyoti Balhara, et al.
Published: (2014-01-01)

Crosstalk between Inflammation and ROCK/MLCK Signaling Pathways in Gastrointestinal Disorders with Intestinal Hyperpermeability
by: Lijun Du, et al.
Published: (2016-01-01)

Study on the effect of PKC-ζ in SDF-1α/CXCR4 axis induced migration of rat bone marrow mesenchymal stem cells
by: Hui Liu, et al.
Published: (2016-10-01)

miR-203 inhibits cell proliferation and migration of lung cancer cells by targeting PKCα.
by: Chen Wang, et al.
Published: (2013-01-01)

Dissecting compartmentalised atypical PKC controls in cell migration
by: Peel, N. R.
Published: (2014)

Calcitonin Induces Bone Formation by Increasing Expression of Wnt10b in Osteoclasts in Ovariectomy-Induced Osteoporotic Rats
by: Chen-Yuan Hsiao, et al.
Published: (2020-09-01)

Role of IgE in modulating the expression and function of smMLCK in human airway smooth muscle cells
by: Balhara, Jyoti
Published: (2012)

Role of IgE in modulating the expression and function of smMLCK in human airway smooth muscle cells
by: Balhara, Jyoti
Published: (2012)

Effects of Target Protein Peptides and MLCK on Calcium Exchange With Calmodulin and the Disulfide-Bond-Locked Mutant Calmodulin's /
by: Snyder, Christopher H.
Published: (1996)

Effect of Electroacupuncture on Bladder Dysfunction via Regulation of MLC and MLCK Phosphorylation in a Rat Model of Type 2 Diabetes Mellitus
by: Xuke Han, et al.
Published: (2021-01-01)

Early Intervention of Didang Decoction on MLCK Signaling Pathways in Vascular Endothelial Cells of Type 2 Diabetic Rats
by: Shoujiao Ye, et al.
Published: (2016-01-01)

Baicalin attenuates angiotensin II-induced blood pressure elevation and modulates MLCK/p-MLC signaling pathway
by: Huixin Liu, et al.
Published: (2021-11-01)

Undifferentiated Wharton's Jelly Mesenchymal Stem Cell Transplantation Induces Insulin-Producing Cell Differentiation and Suppression of T-Cell-Mediated Autoimmunity in Nonobese Diabetic Mice
by: Pei-Jiun Tsai, et al.
Published: (2015-08-01)

Immunosuppressant MPA Modulates Tight Junction through Epigenetic Activation of MLCK/MLC-2 Pathway via p38MAPK
by: Niamat Khan, et al.
Published: (2015-12-01)

Expressions of PKCα, PKCε and PKCδ in cervical cancer and their relationships with chemosensitivity
by: Qing-Zhi Guo
Published: (2019-01-01)

IL-1β promotes mesenchymal stem cell migration by inducing the expression of MMP1
by: Ming-Siou Chen, et al.
Published: (2013)

Salvianolic acid B restored impaired barrier function via downregulation of MLCK by microRNA-1 in rat inflammatory bowel disease
by: Yongjian eXiong, et al.
Published: (2016-05-01)

Role of PKCε in the epithelial-mesenchymal transition induced by FGFR2 isoform switch
by: Danilo Ranieri, et al.
Published: (2020-05-01)

Aurora B but not rho/MLCK signaling is required for localization of diphosphorylated myosin II regulatory light chain to the midzone in cytokinesis.
by: Tomo Kondo, et al.
Published: (2013-01-01)

Myosin Light Chain Kinase (MLCK) Gene Influences Exercise Induced Muscle Damage during a Competitive Marathon.
by: Juan Del Coso, et al.
Published: (2016-01-01)

Folic acid modifies the shape of epithelial cells during morphogenesis via a Folr1 and MLCK dependent mechanism
by: Jessica B. Martin, et al.
Published: (2019-01-01)

Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction
by: Jinyao Jiang, et al.
Published: (2020-09-01)

Enterohemorrhagic Escherichia coli Effector Protein EspF Interacts With Host Protein ANXA6 and Triggers Myosin Light Chain Kinase (MLCK)-Dependent Tight Junction Dysregulation
by: Ying Hua, et al.
Published: (2020-12-01)

Il ruolo della PKCε nel differenziamento eritroide e megacariocitario
by: Gobbi, Giuliana <1971>
Published: (2007)

Regulation of PKC-induced COX2 and IL-8 expression by bufalin in human breast cancer cells
by: Hsiao-Ting Chen, et al.
Published: (2012)

Correction: Myosin Light Chain Kinase (MLCK) Gene Influences Exercise Induced Muscle Damage during a Competitive Marathon.
by: Juan Del Coso, et al.
Published: (2016-01-01)

Chlorogenic acid enhances intestinal barrier by decreasing MLCK expression and promoting dynamic distribution of tight junction proteins in colitic rats
by: Zheng Ruan, et al.
Published: (2016-10-01)

An investigation of PKC isoform functional specificity
by: Kostelecky, B. D.
Published: (2009)

An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation.
by: Carine Rosse, et al.
Published: (2009-11-01)

Escherichia coli Nissle 1917 Protects Intestinal Barrier Function by Inhibiting NF-κB-Mediated Activation of the MLCK-P-MLC Signaling Pathway
by: Shihao Guo, et al.
Published: (2019-01-01)