miR-326 targets antiapoptotic Bcl-xL and mediates apoptosis in human platelets.

miR-326 targets antiapoptotic Bcl-xL and mediates apoptosis in human platelets.

Platelets play crucial roles in hemostasis, thrombosis, wound healing, inflammation, angiogenesis, and tumor metastases. Because they are anucleated blood cells, platelets lack nuclear DNA, but they do contain mitochondrial DNA, which plays a key role in regulating apoptosis. Recent evidence has sug...

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Bibliographic Details
Main Authors: Shifang Yu, Huicong Huang, Gang Deng, Zuoting Xie, Yincai Ye, Ruide Guo, Xuejiao Cai, Junying Hong, Dingliang Qian, Xiangjing Zhou, Zhihua Tao, Bile Chen, Qiang Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395162?pdf=render

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