Preparation of MSZ Hydrogel and Its Treatment of Colitis

In order to control the release of mesalazine (MSZ) in the gastrointestinal tract to achieve better pharmacological effects in the colon, in this study, MSZ was added to hydroxypropyl-β-cyclodextrin (HP-β-CD) to form a water-soluble HP-β-CD/MSZ inclusion complex. Then, the inclusion compound was loa...

Full description

Bibliographic Details
Main Authors: Yanhong Wu, Shangyong Li, Mengfei Jin, Dandan Li, Zihan Zhou, Haiqing Hou, Yantao Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Pharmacology
Subjects:
MSZ
ALG
CS
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.706401/full