Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?

<p>Human breast cancer represents a group of highly heterogeneous lesions consisting of about 20 morphologically and immnohistochemically distinct subtypes with substantially different prognoses. Our recent studies have suggested that all breast cancer subtypes, however, may share a common pat...

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Main Author: Yan-gao Man
Format: Article
Language:English
Published: Ivyspring International Publisher 2010-01-01
Series:Journal of Cancer
Online Access:http://www.jcancer.org/v01p0032.htm
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spelling doaj-688fa293e1164f5b8059c8ee9e6344ab2020-11-24T22:47:19ZengIvyspring International PublisherJournal of Cancer1837-96642010-01-01113237Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?Yan-gao Man<p>Human breast cancer represents a group of highly heterogeneous lesions consisting of about 20 morphologically and immnohistochemically distinct subtypes with substantially different prognoses. Our recent studies have suggested that all breast cancer subtypes, however, may share a common pathway, tumor cell budding from focally disrupted tumor capsules, for their invasion. The potential mechanisms and clinical implications of our observations are discussed.</p>http://www.jcancer.org/v01p0032.htm
collection DOAJ
language English
format Article
sources DOAJ
author Yan-gao Man
spellingShingle Yan-gao Man
Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?
Journal of Cancer
author_facet Yan-gao Man
author_sort Yan-gao Man
title Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?
title_short Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?
title_full Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?
title_fullStr Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?
title_full_unstemmed Tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?
title_sort tumor cell budding from focally disrupted tumor capsules: a common pathway for all breast cancer subtype derived invasion?
publisher Ivyspring International Publisher
series Journal of Cancer
issn 1837-9664
publishDate 2010-01-01
description <p>Human breast cancer represents a group of highly heterogeneous lesions consisting of about 20 morphologically and immnohistochemically distinct subtypes with substantially different prognoses. Our recent studies have suggested that all breast cancer subtypes, however, may share a common pathway, tumor cell budding from focally disrupted tumor capsules, for their invasion. The potential mechanisms and clinical implications of our observations are discussed.</p>
url http://www.jcancer.org/v01p0032.htm
work_keys_str_mv AT yangaoman tumorcellbuddingfromfocallydisruptedtumorcapsulesacommonpathwayforallbreastcancersubtypederivedinvasion
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