Infiltration of M2 Tumor-Associated Macrophages in Oral Squamous Cell Carcinoma Correlates with Tumor Malignancy

Infiltration of M2 Tumor-Associated Macrophages in Oral Squamous Cell Carcinoma Correlates with Tumor Malignancy

Tumor-associated macrophages (TAMs) are a major cellular component in the tumor microenvironment of many solid tumors. The functional competence of TAMs varies depending on the type of tumors and their respective microenvironments. The classically activated M1 macrophages exhibit antitumor functions...

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Bibliographic Details
Main Authors: Jun Shimada, Miki Hiroi, Kazumasa Mori, Yoshihiro Ohmori
Format: Article
Language:English
Published: MDPI AG 2011-09-01
Series:Cancers
Subjects:
tumor-associated macrophage
M2 macrophage
alternatively activated macrophages
oral squamous cell carcinoma
immunohistochemical analysis
CD163
tumor microenvironment
Online Access:http://www.mdpi.com/2072-6694/3/4/3726/

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http://www.mdpi.com/2072-6694/3/4/3726/

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