Arginine metabolism and deprivation in cancer therapy
Certain cancer cells with nutrient auxotrophy and have a much higher nutrient demand compared with normal human cells. Arginine as a versatile amino acid, has multiple biological functions in metabolic and signaling pathways. Depletion of this amino acid by arginine depletor is generally well tolera...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-10-01
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Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332219325557 |