Induction of Donor-Specific Transplantation Tolerance to Skin and Cardiac Allografts Using Mixed Chimerism in (A + B → A) in Rats

Mixed allogeneic chimerism (A + B → A) was induced in rats by reconstitution of lethally irradiated LEW recipients with a mixture of T-cell depleted (TCD) syngeneic and TCD allogeneic ACI bone marrow. Thirty-seven percent of animals repopulated as stable mixed lymphopoietic chimeras, while the remai...

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Bibliographic Details
Main Authors: Peter M. Markus M.D., Gennaro Selvaggi, Xin Cai, John J. Fung, Thomas E. Starzl
Format: Article
Language:English
Published: SAGE Publishing 1993-07-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368979300200418