Knockdown of lncRNA MALAT1 Alleviates LPS-Induced Acute Lung Injury via Inhibiting Apoptosis Through the miR-194-5p/FOXP2 Axis

Knockdown of lncRNA MALAT1 Alleviates LPS-Induced Acute Lung Injury via Inhibiting Apoptosis Through the miR-194-5p/FOXP2 Axis

PurposeWe aimed to identify and verify the key genes and lncRNAs associated with acute lung injury (ALI) and explore the pathogenesis of ALI. Research showed that lower expression of the lncRNA metastasis-associated lung carcinoma transcript 1 (MALAT1) alleviates lung injury induced by lipopolysacch...

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Bibliographic Details
Main Authors: Chuan-chuan Nan, Ning Zhang, Kenneth C. P. Cheung, Hua-dong Zhang, Wei Li, Cheng-ying Hong, Huai-sheng Chen, Xue-yan Liu, Nan Li, Lixin Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
MALAT1
FOXP2
miR-194-5p
apoptosis
acute lung injury
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.586869/full

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