An exo-cell assay for examining real-time γ-secretase activity and inhibition

An exo-cell assay for examining real-time γ-secretase activity and inhibition

<p>Abstract</p> <p>γ-Secretase is an aspartyl protease that cleaves multiple substrates that are involved in broad biological processes ranging from stem cell development to neurodegeneration. The investigation of γ-secretase has been limited by currently available assays that requ...

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Bibliographic Details
Main Authors:	Tian Yuan, Shelton Christopher C, Frattini Mark G, Li Yue-Ming
Format:	Article
Language:	English
Published:	BMC 2009-06-01
Series:	Molecular Neurodegeneration
Online Access:	http://www.molecularneurodegeneration.com/content/4/1/22

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