NOX4-dependent Hydrogen Peroxide Overproduction in Human Atrial Fibrillation and HL-1 Atrial Cells: Relationship to Hypertension

NOX4-dependent Hydrogen Peroxide Overproduction in Human Atrial Fibrillation and HL-1 Atrial Cells: Relationship to Hypertension

Background/Objectives: Atrial fibrillation (AF) is the most common type of cardiac arrhythmia with patients dying frequently of stroke. In view of the unclear etiologies of AF and a potential role of oxidative stress, the present study examined cardiac ROS production and NADPH oxidase (NOX) express...

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Bibliographic Details
Main Authors: Jun eZhang, Ji Youn eYoun, Antony eKim, Rafael eRamire, Ling eGao, Doan eNgo, Jennifer eScovotti, Aman eMahajan, Hua Linda Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Physiology
Subjects:
Angiotensin II
Hypertension
NADPH Oxidase
atrial fibrillation (AF)
hydrogen peroxide (H2O2)
NOX4
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00140/full

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