A TCRβ Repertoire Signature Can Predict Experimental Cerebral Malaria.
Cerebral Malaria (CM) is associated with a pathogenic T cell response. Mice infected by P. berghei ANKA clone 1.49 (PbA) developing CM (CM+) present an altered PBL TCR repertoire, partly due to recurrently expanded T cell clones, as compared to non-infected and CM- infected mice. To analyse the rela...
Main Authors: | Encarnita Mariotti-Ferrandiz, Hang-Phuong Pham, Sophie Dulauroy, Olivier Gorgette, David Klatzmann, Pierre-André Cazenave, Sylviane Pied, Adrien Six |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4742225?pdf=render |
Similar Items
-
The past, present and future of immune repertoire biology – the rise of next-generation repertoire analysis
by: Adrien eSix, et al.
Published: (2013-11-01) -
RepSeq Data Representativeness and Robustness Assessment by Shannon Entropy
by: Wahiba Chaara, et al.
Published: (2018-05-01) -
T follicular helper and T follicular regulatory cells have different TCR specificity
by: Ana Raquel Maceiras, et al.
Published: (2017-04-01) -
Endogenous TCR recombination in TCR Tg single RAG-deficient mice uncovered by robust in vivo T cell activation and selection.
by: Caroline Montaudouin, et al.
Published: (2010-01-01) -
Immunopathogenic CSF TCR repertoire signatures in virus-associated neurologic disease
by: Satoshi Nozuma, et al.
Published: (2021-02-01)