The Role of Notch and Wnt Signaling in MSC Communication in Normal and Leukemic Bone Marrow Niche

The Role of Notch and Wnt Signaling in MSC Communication in Normal and Leukemic Bone Marrow Niche

Notch and Wnt signaling are highly conserved intercellular communication pathways involved in developmental processes, such as hematopoiesis. Even though data from literature support a role for these two pathways in both physiological hematopoiesis and leukemia, there are still many controversies co...

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Bibliographic Details
Main Authors: Paul Takam Kamga, Riccardo Bazzoni, Giada Dal Collo, Adriana Cassaro, Ilaria Tanasi, Anna Russignan, Cristina Tecchio, Mauro Krampera
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Mesenchymal stromal cells
Notch
Wnt
leukemia
bone marrow niche
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.599276/full

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