Propionyl-L-carnitine corrects metabolic and cardiovascular alterations in diet-induced obese mice and improves liver respiratory chain activity.
AIMS: Obesity is a primary contributor to acquired insulin resistance leading to the development of type 2 diabetes and cardiovascular alterations. The carnitine derivate, propionyl-L-carnitine (PLC), plays a key role in energy control. Our aim was to evaluate metabolic and cardiovascular effects of...
Main Authors: | Carmen Mingorance, Lucie Duluc, Matthieu Chalopin, Gilles Simard, Pierre-Henri Ducluzeau, Maria Dolores Herrera, Maria Alvarez de Sotomayor, Ramaroson Andriantsitohaina |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3311627?pdf=render |
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