Propionyl-L-carnitine corrects metabolic and cardiovascular alterations in diet-induced obese mice and improves liver respiratory chain activity.

Propionyl-L-carnitine corrects metabolic and cardiovascular alterations in diet-induced obese mice and improves liver respiratory chain activity.

AIMS: Obesity is a primary contributor to acquired insulin resistance leading to the development of type 2 diabetes and cardiovascular alterations. The carnitine derivate, propionyl-L-carnitine (PLC), plays a key role in energy control. Our aim was to evaluate metabolic and cardiovascular effects of...

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Bibliographic Details
Main Authors: Carmen Mingorance, Lucie Duluc, Matthieu Chalopin, Gilles Simard, Pierre-Henri Ducluzeau, Maria Dolores Herrera, Maria Alvarez de Sotomayor, Ramaroson Andriantsitohaina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3311627?pdf=render

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http://europepmc.org/articles/PMC3311627?pdf=render

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