Foxf2 plays a dual role during transforming growth factor beta-induced epithelial to mesenchymal transition by promoting apoptosis yet enabling cell junction dissolution and migration

Foxf2 plays a dual role during transforming growth factor beta-induced epithelial to mesenchymal transition by promoting apoptosis yet enabling cell junction dissolution and migration

Abstract Background The most life-threatening step during malignant tumor progression is reached when cancer cells leave the primary tumor mass and seed metastasis in distant organs. To infiltrate the surrounding tissue and disseminate throughout the body, single motile tumor cells leave the tumor m...

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Bibliographic Details
Main Authors: Nathalie Meyer-Schaller, Chantal Heck, Stefanie Tiede, Mahmut Yilmaz, Gerhard Christofori
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Breast Cancer Research
Subjects:
Apoptosis
Breast cancer
Cell migration
E-cadherin
EGFR
EMT
Online Access:http://link.springer.com/article/10.1186/s13058-018-1043-6

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