Mutations Defining Patient Cohorts With Elevated PD-L1 Expression in Gastric Cancer

The immunotherapy agent pembrolizumab has been approved for gastric cancer (GC) patients with recurrent or advanced disease who are PD-L1 positive. Mutations in the primary lesion may drive the expression of immune targets thereby priming the tumor to therapeutic sensitivity. In this study, we aimed...

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Bibliographic Details
Main Authors: Otília Menyhárt, Lőrinc Sándor Pongor, Balázs Győrffy
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Pharmacology
Subjects:
TTK
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01522/full

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