Retroviral Integration Site Selection
The stable insertion of a copy of their genome into the host cell genome is an essential step of the life cycle of retroviruses. The site of viral DNA integration, mediated by the viral-encoded integrase enzyme, has important consequences for both the virus and the host cell. The analysis of retrovi...
Main Authors: | Angela Ciuffi, Sébastien Desfarges |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2010-01-01
|
Series: | Viruses |
Subjects: | |
Online Access: | http://www.mdpi.com/1999-4915/2/1/111/ |
Similar Items
-
Régulation de l'intégration du VIH-1 par la protéine TOX4, la transcription et la topologie de l'ADN cellulaire
by: Xavier, Johan
Published: (2014) -
Impact of LEDGIN treatment during virus production on residual HIV-1 transcription
by: Gerlinde Vansant, et al.
Published: (2019-04-01) -
Strategies for Targeting Retroviral Integration for Safer Gene Therapy: Advances and Challenges
by: Kristine E. Yoder, et al.
Published: (2021-05-01) -
The selenium-containing drug ebselen potently disrupts LEDGF/p75-HIV-1 integrase interaction by targeting LEDGF/p75
by: Da-Wei Zhang, et al.
Published: (2020-01-01) -
Insight in HIV Integration Site Selection Provides a Block-and-Lock Strategy for a Functional Cure of HIV Infection
by: Zeger Debyser, et al.
Published: (2018-12-01)