Dosimetric impact of amino acid positron emission tomography imaging for target delineation in radiation treatment planning for high-grade gliomas

Background and purpose: The amino-acid positron emission tomography (PET) tracer 3,4-dihydroxy-6-[18F] fluoro-l-phenylalanine (18F-DOPA) has increased sensitivity for detecting regions of biologically aggressive tumors compared to T1 contrast-enhanced (T1-CE) magnetic resonance imaging (MRI). We per...

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Bibliographic Details
Main Authors: Tomas Kazda, Deanna H. Pafundi, Alan Kraling, Thomas Bradley, Val J. Lowe, Debra H. Brinkmann, Nadia N. Laack
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Physics and Imaging in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405631616300148