Divergent Effects of Cyclophilin-D Inhibition on the Female Rat Heart: Acute Versus Chronic Post-Myocardial Infarction

Divergent Effects of Cyclophilin-D Inhibition on the Female Rat Heart: Acute Versus Chronic Post-Myocardial Infarction

Background/Aims: The mitochondrial permeability transition pore opening plays a critical role in the pathogenesis of myocardial infarction. Inhibition of cyclophilin-D (CyP-D), a key regulator of the mitochondrial permeability transition pore, has been shown to exert cardioprotective effects against...

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Bibliographic Details
Main Authors: Rebecca M. Parodi-Rullán, Jadira Soto-Prado, Jesús Vega-Lugo, Xavier Chapa-Dubocq, Sara I. Díaz-Cordero, Sabzali  Javadov
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-10-01
Series:Cellular Physiology and Biochemistry
Subjects:
Myocardial infarction
Reperfusion
Mitochondrial permeability transition
Cyclophilin D
Cardioprotection
Sanglifehrin A
Online Access:https://www.karger.com/Article/FullText/494006

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https://www.karger.com/Article/FullText/494006

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