Poly (ADP-ribose) polymerase plays an important role in intermittent hypoxia-induced cell death in rat cerebellar granule cells

Poly (ADP-ribose) polymerase plays an important role in intermittent hypoxia-induced cell death in rat cerebellar granule cells

<p>Abstract</p> <p>Background</p> <p>Episodic cessation of airflow during sleep in patients with sleep apnea syndrome results in intermittent hypoxia (IH). Our aim was to investigate the effects of IH on cerebellar granule cells and to identify the mechanism of IH-induc...

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Bibliographic Details
Main Authors: Chiu Sheng-Chun, Huang Sung-Ying, Tsai Yu-Chieh, Chen Shee-Ping, Pang Cheng-Yoong, Lien Chih-Feng, Lin Yu-Jou, Yang Kun-Ta
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Journal of Biomedical Science
Subjects:
Intermittent hypoxia
Oxidative stress
Poly (ADP-ribose) polymerase
Calpain
Cerebellar granule cell
Online Access:http://www.jbiomedsci.com/content/19/1/29

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