Microbial biofilm correlates with an increased antibiotic tolerance and poor therapeutic outcome in infective endocarditis
Abstract Background Infective endocarditis (IE) is associated with high rates of mortality. Prolonged treatments with high-dose intravenous antibiotics often fail to eradicate the infection, frequently leading to high-risk surgical intervention. By providing a mechanism of antibiotic tolerance, whic...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-10-01
|
| Series: | BMC Microbiology |
| Online Access: | http://link.springer.com/article/10.1186/s12866-019-1596-2 |