New Prostate Cancer Targets for Diagnosis, Imaging, and Therapy: Focus on Prostate-Specific Membrane Antigen

New Prostate Cancer Targets for Diagnosis, Imaging, and Therapy: Focus on Prostate-Specific Membrane Antigen

The rising incidence rate of the cancer in the prostate gland has increased the demand for improved diagnostic, imaging, and therapeutic approaches. Prostate-specific membrane antigen (PSMA), with folate hydrolase and carboxypeptidase and, internalization activities, is highly expressed in the epith...

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Bibliographic Details
Main Authors: Alessia Cimadamore, Monica Cheng, Matteo Santoni, Antonio Lopez-Beltran, Nicola Battelli, Francesco Massari, Andrea B. Galosi, Marina Scarpelli, Rodolfo Montironi
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Oncology
Subjects:
prostate cancer
prostate-specific membrane antigen
PSMA
small molecule inhibitors
RNA aptamer conjugates
PSMA-based immunotherapy
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00653/full

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