Nuclear trafficking of secreted factors and cell-surface receptors: new pathways to regulate cell proliferation and differentiation, and involvement in cancers
<p>Abstract</p> <p>Secreted factors and cell surface receptors can be internalized by endocytosis and translocated to the cytoplasm. Instead of being recycled or proteolysed, they sometimes translocate to the nucleus. Nuclear import generally involves a nuclear localization signal...
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| Format: | Article |
| Language: | English |
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BMC
2006-10-01
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| Series: | Cell Communication and Signaling |
| Online Access: | http://www.biosignaling.com/content/4/1/7 |