A Dense Fibrillar Collagen Scaffold Differentially Modulates Secretory Function of iPSC-Derived Vascular Smooth Muscle Cells to Promote Wound Healing

A Dense Fibrillar Collagen Scaffold Differentially Modulates Secretory Function of iPSC-Derived Vascular Smooth Muscle Cells to Promote Wound Healing

The application of human-induced pluripotent stem cells (hiPSCs) to generate vascular smooth muscle cells (hiPSC-VSMCs) in abundance is a promising strategy for vascular regeneration. While hiPSC-VSMCs have already been utilized for tissue-engineered vascular grafts and disease modeling, there is a...

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Bibliographic Details
Main Authors: Biraja C. Dash, Ocean Setia, Jolanta Gorecka, Hassan Peyvandi, Kaiti Duan, Lara Lopes, James Nie, Francois Berthiaume, Alan Dardik, Henry C. Hsia
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
induced pluripotent stem cell
vascular smooth muscle cell
wound healing
paracrine factors
angiogenesis
inflammation
Online Access:https://www.mdpi.com/2073-4409/9/4/966

Internet

https://www.mdpi.com/2073-4409/9/4/966

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