High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria.

Recently developed technologies have enabled multi-well measurement of O(2) consumption, facilitating the rate of mitochondrial research, particularly regarding the mechanism of action of drugs and proteins that modulate metabolism. Among these technologies, the Seahorse XF24 Analyzer was designed f...

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Bibliographic Details
Main Authors: George W Rogers, Martin D Brand, Susanna Petrosyan, Deepthi Ashok, Alvaro A Elorza, David A Ferrick, Anne N Murphy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3143121?pdf=render