The effect of lipoprotein-associated phospholipase A<sub>2</sub> deficiency on pulmonary allergic responses in <it>aspergillus fumigatus</it> sensitized mice

The effect of lipoprotein-associated phospholipase A<sub>2</sub> deficiency on pulmonary allergic responses in <it>aspergillus fumigatus</it> sensitized mice

<p>Abstract</p> <p>Background</p> <p>Lipoprotein-associated phospholipase A<sub>2</sub> (Lp-PLA<sub>2</sub>)/platelet-activating factor acetylhydrolase (PAF-AH) has been implicated in the pathogenesis of cardiovascular disease. A therapeutic targ...

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Bibliographic Details
Main Authors: Jiang Zhilong, Fehrenbach Melane L, Ravaioli Giulia, Kokalari Blerina, Redai Imre G, Sheardown Steven A, Wilson Stephen, Macphee Colin, Haczku Angela
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Respiratory Research
Subjects:
Lp-PLA<sub>2</sub>
PAF-AH
Knock-out mice
Airway inflammation
IgE
Mast cells
Degranulation
Online Access:http://respiratory-research.com/content/13/1/100

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http://respiratory-research.com/content/13/1/100

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