Intracellular calcium signaling and phospho-antigen measurements reveal functional proximal TCR activation in lymphocytes from septic shock patients

Intracellular calcium signaling and phospho-antigen measurements reveal functional proximal TCR activation in lymphocytes from septic shock patients

Bibliographic Details
Main Authors: Charles de Roquetaillade, Khalil Kandara, Morgane Gossez, Estelle Peronnet, Céline Monard, Martin Cour, Thomas Rimmelé, Laurent Argaud, Guillaume Monneret, Fabienne Venet
Format: Article
Language:English
Published: SpringerOpen 2019-12-01
Series:Intensive Care Medicine Experimental
Online Access:https://doi.org/10.1186/s40635-019-0287-5
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spelling doaj-67fe2fc38f6342b3bf0a9879823ae3802020-12-27T12:20:49ZengSpringerOpenIntensive Care Medicine Experimental2197-425X2019-12-01711410.1186/s40635-019-0287-5Intracellular calcium signaling and phospho-antigen measurements reveal functional proximal TCR activation in lymphocytes from septic shock patientsCharles de Roquetaillade0Khalil Kandara1Morgane Gossez2Estelle Peronnet3Céline Monard4Martin Cour5Thomas Rimmelé6Laurent Argaud7Guillaume Monneret8Fabienne Venet9EA 7426, Pathophysiology of Injury-Induced Immunosuppression (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Edouard Herriot HospitalEA 7426, Pathophysiology of Injury-Induced Immunosuppression (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Edouard Herriot HospitalEA 7426, Pathophysiology of Injury-Induced Immunosuppression (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Edouard Herriot HospitalEA 7426, Pathophysiology of Injury-Induced Immunosuppression (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Edouard Herriot HospitalAnesthesia and Critical Care Medicine Department, Hospices Civils de Lyon, Edouard Herriot HospitalIntensive Care Medicine Department, Hospices Civils de Lyon, Edouard Herriot HospitalEA 7426, Pathophysiology of Injury-Induced Immunosuppression (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Edouard Herriot HospitalIntensive Care Medicine Department, Hospices Civils de Lyon, Edouard Herriot HospitalEA 7426, Pathophysiology of Injury-Induced Immunosuppression (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Edouard Herriot HospitalEA 7426, Pathophysiology of Injury-Induced Immunosuppression (Université Claude Bernard Lyon 1 - Hospices Civils de Lyon - bioMérieux), Edouard Herriot Hospitalhttps://doi.org/10.1186/s40635-019-0287-5
collection DOAJ
language English
format Article
sources DOAJ
author Charles de Roquetaillade
Khalil Kandara
Morgane Gossez
Estelle Peronnet
Céline Monard
Martin Cour
Thomas Rimmelé
Laurent Argaud
Guillaume Monneret
Fabienne Venet
spellingShingle Charles de Roquetaillade
Khalil Kandara
Morgane Gossez
Estelle Peronnet
Céline Monard
Martin Cour
Thomas Rimmelé
Laurent Argaud
Guillaume Monneret
Fabienne Venet
Intracellular calcium signaling and phospho-antigen measurements reveal functional proximal TCR activation in lymphocytes from septic shock patients
Intensive Care Medicine Experimental
author_facet Charles de Roquetaillade
Khalil Kandara
Morgane Gossez
Estelle Peronnet
Céline Monard
Martin Cour
Thomas Rimmelé
Laurent Argaud
Guillaume Monneret
Fabienne Venet
author_sort Charles de Roquetaillade
title Intracellular calcium signaling and phospho-antigen measurements reveal functional proximal TCR activation in lymphocytes from septic shock patients
title_short Intracellular calcium signaling and phospho-antigen measurements reveal functional proximal TCR activation in lymphocytes from septic shock patients
title_full Intracellular calcium signaling and phospho-antigen measurements reveal functional proximal TCR activation in lymphocytes from septic shock patients
title_fullStr Intracellular calcium signaling and phospho-antigen measurements reveal functional proximal TCR activation in lymphocytes from septic shock patients
title_full_unstemmed Intracellular calcium signaling and phospho-antigen measurements reveal functional proximal TCR activation in lymphocytes from septic shock patients
title_sort intracellular calcium signaling and phospho-antigen measurements reveal functional proximal tcr activation in lymphocytes from septic shock patients
publisher SpringerOpen
series Intensive Care Medicine Experimental
issn 2197-425X
publishDate 2019-12-01
url https://doi.org/10.1186/s40635-019-0287-5
work_keys_str_mv AT charlesderoquetaillade intracellularcalciumsignalingandphosphoantigenmeasurementsrevealfunctionalproximaltcractivationinlymphocytesfromsepticshockpatients
AT khalilkandara intracellularcalciumsignalingandphosphoantigenmeasurementsrevealfunctionalproximaltcractivationinlymphocytesfromsepticshockpatients
AT morganegossez intracellularcalciumsignalingandphosphoantigenmeasurementsrevealfunctionalproximaltcractivationinlymphocytesfromsepticshockpatients
AT estelleperonnet intracellularcalciumsignalingandphosphoantigenmeasurementsrevealfunctionalproximaltcractivationinlymphocytesfromsepticshockpatients
AT celinemonard intracellularcalciumsignalingandphosphoantigenmeasurementsrevealfunctionalproximaltcractivationinlymphocytesfromsepticshockpatients
AT martincour intracellularcalciumsignalingandphosphoantigenmeasurementsrevealfunctionalproximaltcractivationinlymphocytesfromsepticshockpatients
AT thomasrimmele intracellularcalciumsignalingandphosphoantigenmeasurementsrevealfunctionalproximaltcractivationinlymphocytesfromsepticshockpatients
AT laurentargaud intracellularcalciumsignalingandphosphoantigenmeasurementsrevealfunctionalproximaltcractivationinlymphocytesfromsepticshockpatients
AT guillaumemonneret intracellularcalciumsignalingandphosphoantigenmeasurementsrevealfunctionalproximaltcractivationinlymphocytesfromsepticshockpatients
AT fabiennevenet intracellularcalciumsignalingandphosphoantigenmeasurementsrevealfunctionalproximaltcractivationinlymphocytesfromsepticshockpatients
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