Identification of Specific Joint-Inflammatogenic Cell-Free DNA Molecules From Synovial Fluids of Patients With Rheumatoid Arthritis

Identification of Specific Joint-Inflammatogenic Cell-Free DNA Molecules From Synovial Fluids of Patients With Rheumatoid Arthritis

Elevated cell-free DNA (cfDNA) levels in the plasma and synovial fluid of rheumatoid arthritis (RA) patients are proposed to be pathologically relevant. However, direct evidence to support this perception is lacking, and molecular feature of the cfDNA molecules with assumed pathological function is...

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Bibliographic Details
Main Authors: Cong Dong, Yu Liu, Chengxin Sun, Huiyi Liang, Lie Dai, Jun Shen, Song Wei, Shixin Guo, Kam W. Leong, Yongming Chen, Lai Wei, Lixin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
autoimmunity
cell-free DNA
CpG-motif
inflammation
rheumatoid arthritis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00662/full

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