Phenotypic evolutionary models in stem cell biology: replacement, quiescence, and variability.

Phenotypic evolutionary models have been used with great success in many areas of biology, but thus far have not been applied to the study of stem cells except for investigations of cancer. We develop a framework that allows such modeling techniques to be applied to stem cells more generally. The fu...

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Bibliographic Details
Main Authors: Marc Mangel, Michael B Bonsall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2217616?pdf=render